Category Archives: Detection
Optical Resolution and Protein Drop Imaging
When I think about the optical resolution capabilities of a microscope designed for protein drop imaging, I think about the smallest size crystal I could possibly resolve. And in fact, Wikipedia defines optical resolution as “the ability of an imaging … Continue reading
Art Robbins Hanging Drop Seal Tested for UV Microscopy
UV imaging is a great technique to detect protein crystals under difficult imaging conditions (precipitates, membrane screens, etc), but it requires some extra care when it comes to selecting crystallization plates and seals. The issue is that plates or seals … Continue reading
UV microscopy in protein crystallization: Resolution vs. Detection
Our last post about UV microscopy was all about optical resolution. We used protein needle crystals to get an idea what smallest size protein crystal would be that that we could resolve with our new imager. Of course we were … Continue reading
Resolve This!
This has been the main challenge to our engineering team over the last year or so: Build a combined UV/visible microscope with one specialized purpose: Allow for the reliable detection of protein crystals. UV light has a particular advantage for … Continue reading
